
一、个人简介
王善之,国家级青年人才,植物病理学系研究员,博士研究生导师。主要从事水稻-病原细菌互作机制和抗病育种研究。近年来,揭示了水稻病原细菌多个毒力因子的致病机理,并提出“抗营养”等作物抗病新思路。以第一(含共同)或共同通讯作者身份在Science(2025)、Nat. Commun.(2021)、Sci. Signal.(2021)、Mol. Plant(2015)等期刊发表多篇研究论文。主持国家自然科学基金青年项目(B类)、面上项目等。授权国家发明专利2项。担任Plant Physiol.、J. Exp. Bot.等期刊审稿人。课题组氛围融洽,鼓励不同学术观点的思想碰撞与自由探索,欢迎感兴趣的本科生和研究生加入。
二、教育和工作经历
2008 - 2012 中国农业大学植保学院,本科
2012 - 2017 中国农业大学植保学院,博士
2017 - 2022 中国农业大学植保学院,博士后
2022 - 至今 英国上市公司365植保学院,研究员
三、研究方向
1. 解析病原细菌致病分子机制,包括如何抑制寄主免疫、获取营养等
2. 发掘作物抗病信号通路,培育作物抗病新种质
3. 揭示作物-病原细菌-环境微生物互作机制,开发作物生物防治手段
四、科研项目
1. 国家自然科学基青年项目(B类),2027-2029,200万,主持
2. 国家自然科学基金面上项目,2024/01-2027/12,50万,主持
3. 英国上市公司365含弘研究员人才引进项目,2022-2027,200万,主持
4. 国家自然科学基金青年项目,2019-2020,26万,主持,已结题
五、代表性研究论文(“#”共同第一作者, “*”通讯作者)
1. Wang S. *, Zhu L., Tian M., et al. (2025). A bacterial nutrition strategy for plant disease control. Science. 390, 1299–1304. (独立一作,共同通讯作者)
2. Wang, S., Li, S., Wang, J., et al. (2021). A bacterial kinase phosphorylates OSK1 to suppress stomatal immunity in rice. Nature Communications 12, 5479. (独立一作)
3. Wang, S.#, Sun, Z.#, Wang, H., et al. (2015). Rice OsFLS2-mediated perception of bacterial flagellins is evaded by Xanthomonas oryzae pvs. oryzae and oryzicola. Molecular Plant 8, 1024-1037. (共同一作)
4. Wei, C.#, Wang S.#, Liu P., et al. (2021). The PdeK-PdeR two-component system promotes unipolar localization of FimX and pilus extension in Xanthomonas oryzae pv. oryzicola. Science Signaling 14, 700. (共同一作)
六、其他论文
1. Zheng X., Fang A., Qiu S., Zhao G., Wang J., Wang S., Wei J., Gao H., Yang J., Mou B., Cui F., Zhang J., Liu J., and Sun W. (2022). Ustilaginoidea virens secretes a family of phosphatases that stabilize the negative immune regulator OsMPK6 and suppress plant immunity. The Plant Cell. 34(8),3088-3109.
2. Yang J., Zhang N., Wang J., Fang A., Fan J., Li D., Li Y., Wang S., Cui F., Yu J., Liu Y., Wang W.M., Peng Y.L., He S.Y., and Sun W. (2022). SnRK1A-mediated phosphorylation of a cytosolic ATPase positively regulates rice innate immunity and is inhibited by Ustilaginoidea virens effector SCRE1. New Phytologist. doi: 10.1111/nph.18460.
3. Muhammad T.#, Mateen, A.#, Wang S., Qiu S., Zheng X., Zhang J., Bhadauria V., and Sun, W. (2021). Versatile effectors of phytopathogenic fungi target host immunity. Journal of Integrative Plant Biology https://doi.org/10.1111/jipb.13162.
4. Zhang, N.#, Yang, J., Fang, A., Wang, J., Li, D., Li, Y., Wang, S., Cui, F., Yu, J., Liu, Y., Peng Y-L, and Sun W. (2020). The essential effector SCRE1 in Ustilaginoidea virens suppresses rice immunity via a small peptide region. Molecular Plant Pathology 21,445-459.
5. Wang J.#, Wang S., Hu K., Yang J., Xin X., Zhou W., Fan J., Cui F., Mou B., Zhang S., Wang G. L., and Sun W. (2018). The kinase OsCPK4 regulates a buffering mechanism that fine-tunes innate immunity. Plant Physiology 176, 1835–1849.
6. Liu, L.#, Wang, Y., Cui, F., Fang, A., Wang, S., Wang, J., Wei, C., Li, S., and Sun, W. (2017). The type III effector AvrXccB in Xanthomonas campestris pv. campestris targets putative methyltransferases and suppresses innate immunity in Arabidopsis. Molecular Plant Pathology 18, 768-782.
7. Li, S.#, Wang, Y., Wang, S., Fang, A., Wang, J., Liu, L., Zhang, K., Mao, Y., and Sun, W. (2015). The type III effector AvrBs2 in Xanthomonas oryzae pv. oryzicola suppresses rice immunity and promotes disease development. Molecular Plant-Microbe Interactions 28, 869-880.
8. Lu, F.#, Wang, H., Wang, S., Jiang, W., Shan, C., Li, B., Yang, J., Zhang, S., and Sun, W. (2015). Enhancement of innate immune system in monocot rice by transferring the dicotyledonous elongation factor Tu receptor EFR. Journal of Integrative Plant Biology 57, 641-652
七、授权专利
1. 孙文献; 王善之; 汪激扬; 田猛; 徐嘉擎; 朱立松; 崔福浩 ; 一种环化磷酸糖酯化合物及其应用, 2023-02-12, 中国, CN202310100490.1 (专利)
2. 孙文献; 王善之; 汪激扬; 田猛; 徐嘉擎; 朱立松; 崔福浩 ; 一种抗黄单胞菌属病害相关蛋白及其编码基因与应用, 2023-02-12, 中国, CN202310100491.6 (专利)
本课题组长期招收植物病理学和分子生物学方向的博士后,欢迎有意向的博士沟通联系!
邮箱: 0801080926@cau.edu.cn